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No benefit in antidepressant drug for COVID-19 treatment: Study

FILE - This 2020 electron microscope image provided by the National Institute of Allergy and Infectious Diseases - Rocky Mountain Laboratories shows SARS-CoV-2 virus particles which cause COVID-19, isolated from a patient in the U.S., emerging from the surface of cells cultured in a lab. According to a study released in The Lancet Global Health on Wednesday, Oct. 27, 2021, Fluvoxamine, a cheap antidepressant, reduced the need for hospitalization among high-risk adults with COVID-19. (NIAID-RML via AP)

(NewsNation) — An antidepressant drug that was touted as a cheap treatment now shows no effects for patients with COVID-19, according to a new study. 

In 2021, multiple reports came out suggesting that the pill, called fluvoxamine, reduced the need for hospitalization among high-risk adults with COVID-19. 


Researchers tested the pill used for depression and obsessive-compulsive disorder because it was known to reduce inflammation and looked promising in smaller studies. Now, a JAMA Network study reports it does not shorten the duration of symptoms in adults with mild to moderate COVID-19.  

The clinical trial sought to determine whether a 100 mg dosage of fluvoxamine, taken twice daily for 13 days, could reduce the duration of symptoms in outpatient adults (aged 30 or over) with mild to moderate COVID-19 when compared to a placebo. 


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The trial, which included 1,175 participants enrolled when omicron COVID-19 subvariants were prevalent, found no significant difference in the time to sustained recovery between the fluvoxamine group and the placebo group.  

Fluvoxamine as a treatment was a positive development during the pandemic due to its low cost. It would cost $4 for a course of COVID-19 treatment. By comparison, antibody IV treatments cost about $2,000. 

The Associated Press contributed to this report.