GREEN BAY, Wis. (AP) — Rasul Douglas and the Green Bay Packers’ pass defense didn’t let the Cleveland Browns spoil Aaron Rodgers’ milestone day.

Rodgers surpassed Brett Favre to become Green Bay’s all-time leader in touchdown passes, and the Packers intercepted Baker Mayfield four times in a 24-22 victory over the Cleveland Browns on Saturday. Cleveland nearly came all the way back from a 12-point second-half deficit before Douglas’ second interception of the day sealed the game with 43 seconds left.

“We’ve got to do a better job of closing games out,” Rodgers said. “Our defense has closed out a lot of games, the last two weeks stopping that 2-point conversion (in a 31-30 victory at Baltimore) and Rasul coming up with that big pick. It’s nerve-racking, but winning is difficult in this league.”

Rodgers went 24 of 34 for 202 yards with three touchdown passes to increase his career total to 445. Favre threw 508 touchdown passes during his Hall of Fame career, 442 of them with Green Bay.

But it was Green Bay’s defense that clinched this victory by sacking Mayfield five times and forcing him into his first career four-interception performance. All three touchdowns by the Packers (12-3) came after Mayfield interceptions.

“It was just missed throws,” Mayfield said. “Uncharacteristic, and I hurt this team. That’s the most frustrating thing for me, because I thought our defense played tremendous against a really, really good offense. But when you turn the ball over in your own territory, in the red zone and around midfield and give them extra opportunities, they’re going to take advantage of it.”

Mayfield was 21 of 36 for 222 yards with two touchdowns as well as those four picks in his return from the reserve/COVID-19 list, which caused him to miss a 16-14 loss to the Las Vegas Raiders on Monday.

Nick Chubb ran for 126 yards and a touchdown to lead the Browns’ 219-yard rushing effort that kept them in the game.

The Browns (7-8) trailed 24-22 and had third-and-10 at the 50 when Douglas picked off Mayfield’s pass intended for Donovan Peoples-Jones at the 40.

Since getting signed off the Arizona Cardinals’ practice squad in early October, Douglas has a team-high five interceptions. He had a game-clinching interception in the final minute of a victory at Arizona earlier this season.

“Coaches told me as long as I keep catching them, they’ll keep coming,” Douglas said. “I’m just trying to catch them when they come.”

Darnell Savage and Chandon Sullivan also had interceptions. Rashan Gary had two of the Packers’ five sacks against the Browns, whose offensive line was decimated with left tackle Jedrick Wills and center JC Tretter both on the COVID-19 list.

Until the Browns produced their second-half threat, the day belonged to Rodgers, who broke Favre’s record by throwing an 11-yard TD pass to Allen Lazard in the first quarter.

“Aaron breaks so many records,” Lazard said. “Literally every week it’s almost like I get on Instagram Monday morning and someone’s always posting some new record that Aaron’s breaking. For us, in a sense, it’s another day at the office. Obviously this one’s a bigger milestone in that sense.”

Rodgers spent his first three NFL seasons backing up Favre before taking over in 2008. Favre sent a message to Rodgers in a video that aired on the Lambeau Field scoreboard after the record-breaking touchdown pass.

“Hey, 12, congratulations, man, on passing my touchdown record,” Favre said. “I have one request. Go get us another Super Bowl. Congrats.”

“Definitely got me a little teary-eyed on the bench,” said Rodgers, who saluted the Lambeau Field crowd that gave him a hearty ovation. “A moment I’ll never forget, for sure. I’m thankful for Favre’s message, for the response from the guys and the crowd obviously was really special.”

Rodgers later threw two touchdown passes to Davante Adams, who had 10 catches for 114 yards. Adams has caught at least 10 passes for 100 yards and two touchdowns in eight career games, the most of anyone in NFL history.

Adams has caught 67 touchdown passes from Rodgers, giving them the franchise record for touchdown pass combinations. Rodgers threw 65 touchdown passes to former Packers receiver Jordy Nelson.

“When you start stacking up the numbers for Davante, it’s mind-blowing,” Rodgers said. “I really feel like he’s the best player that I’ve played with.”

The Packers already have clinched the NFC North title and are seeking the conference’s top playoff seed as they chase their first Super Bowl berth since their 2010 championship season. They have lost in the NFC championship game each of the last two seasons.